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Tramadol Information

Generic name: Tramadol (TRAM a dol).
Brand names: Ultram, Ultram ER.

Tramadol fact sheet.

Tramadol is not allowed for use by people with a history of substance abuse or addiction.

Follow the prescription with maximum precision. Never exceed the recommended doses or use Tramadol for a period longer than that advised by your healthcare provider. Maximum daily dose of Tramadol is 300 mg.

Tramadol is habit-forming, which means that a person using it for a long period of time may feel the need to continue taking it even when the period of treatment is over. Sudden stopping of the therapy may trigger a heavy withdrawal effect (anxiety, sweating, nausea, diarrhea, tremors, chills, hallucinations, insomnia, or breathing problems), so you are not advised to try to quit using this medication on your own. Your doctor will decrease your dose of Tramadol little by little, thus helping you to quit easier.

Tramadol is intended for oral use only. Crushing the capsule and inhaling the received powder or injecting the water-based solution containing this powder into the body can cause life-threatening or even fatal side effects.

There have been a number of cases when the patients using Tramadol had seizures (convulsions). A Tramadol consumer with a history of seizures or head injury, or a metabolic disorder is more likely to have a seizure. The effect of some medications such as antidepressants, muscle relaxants, or medicine for nausea and vomiting can increase this dangerous possibility.

A heavy overdose with Tramadol may result in death. If you suspect you have taken too much of Tramadol, seek for emergency medical attention immediately. The most common symptoms of a heavy Tramadol overdose are the following: drowsiness, shallow breathing, slow heartbeat, extreme weakness, cold or clammy skin, the feeling of light-headedness, fainting, or coma. Avoid drinking alcohol or using medications that can cause drowsiness (cold medicine, other pain medications, muscle relaxants, and medicine for seizures, depression or anxiety, etc) together with Tramadol. The interaction of these may slow your breathing or increase sleepiness.

Be careful when you drive, operate heavy machinery or fulfill other potentially hazardous tasks that require you to be awake and alert since some side effects of Tramadol can affect your thinking or reactions by slowing them down.

What is Tramadol?

Tramadol is a prescription pain reliever available in two forms - immediate-release (used in the treatment of moderate to severe pains) and extended-release (used in the treatment of moderate to severe chronic pain).

Please note that this article doesn't list all possible uses of Tramadol. Consult your healthcare provider to learn more about the uses of this medication.

What should I discuss with my healthcare provider before taking Tramadol?

People with the history of substance or alcohol abuse or addiction are not allowed to use Tramadol. Do not take Tramadol if you are under the effect of alcohol or drugs since that can trigger dangerous (possibly even fatal) side effects. The list of potentially dangerous substances includes:

  • alcohol;
  • narcotic pain medicine;
  • sedatives or tranquilizers (such as Valium);
  • medicine for depression or anxiety;
  • medicine for mental illness (bipolar disorder, schizophrenia, etc); or
  • street drugs.

One of the most dangerous side effects of Tramadol is a seizure, which can be triggered by any of the following medical conditions:

  • a history of substance or alcohol abuse or addiction;
  • a history of epilepsy or other seizure disorder;
  • a history of head injury; or
  • a metabolic disorder.

Discuss your individual risk of getting a seizure triggered by Tramadol with your therapist prior to the beginning of the therapy.

Before starting to use Tramadol, inform your doctor about all drugs that you are allergic to, or about the following conditions if you have any:

  • kidney disease;
  • liver disease;
  • a stomach disorder; or
  • a history of depression, mental illness, or suicidal attempt.

In case any of the conditions stated above applies to you, your doctor may forbid you to take Tramadol or at least suggest a dosage adjustment or a series of tests carried out throughout the period of the treatment.

Tramadol is in the FDA pregnancy category C, which means that this medication can possibly harm the fetus in case a pregnant woman takes it. Tramadol can also cause serious or even fatal defects in a newborn baby if the mother used it during pregnancy. Let your doctor know if you are pregnant or are planning to become pregnant in the near future before starting the therapy with Tramadol. Tramadol is known to be able to pass into breast milk, so it can possibly harm a nursing baby. Do not breast-feed a baby if you are using Tramadol. Elderly people can turn out to be much more susceptible to Tramadol. If you are over 65 years of age, your doctor may suggest you lower the dose.

The safety and effectiveness of Tramadol in children under 16 years old have not been tested yet, so you are strongly suggested to avoid giving youngsters the access to this medication.

Tramadol usage directions.

Always take Tramadol in full accordance with the prescription that your therapist gave you. Do not take this medication in larger doses or for a period longer than that stated by your therapist. Follow all the directions on your prescription label precisely. Remember that the maximum daily dose of Tramadol must not exceed 300mg/day. Each Tramadol dose should be taken with a full glass of water, no matter whether you take it with food or not.

Tramadol is intended for oral administration only. Usage of this medication by inhaling or injecting it into your body may lead to serious side effects, overdose or even death, since the active contents of the crushed pill may get assimilated into the body too fast.

In case you are using the extended-release form of Tramadol, you may notice the tablet shells passing into your stools from time to time. However, you shouldn't think that this means that you are not receiving enough of this med. Never try to exceed the dose if such thing happens.

The effect of Tramadol may decrease with time (the effect of tolerance). Tell your doctor if you have noticed that this medication stopped working well to relieve your pain. Never try to change the dose on your own, without noticing your doctor.

Keep Tramadol at room temperature, in a dark dry place, away from excess heat and direct light. Keep it out of the reach of children and away from pets.

What should i do if i miss a dose of Tramadol?

If for some reason you happen to miss a dose of Tramadol, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and keep on taking Tramadol according to your regular schedule. Never try to increase your intake of Tramadol in attempt to catch up with the missed dose(s).

In case of overdose with Tramadol.

An overdose with Tramadol can be fatal, so if you think you might have taken too much of this medication, seek for emergency medical help immediately.

Drowsiness, shallow breathing, slow heartbeat, extraordinary weakness, cold or clammy skin, light-headedness, fainting, or coma are the most common symptoms of a heavy overdose with Tramadol.

Patients taking Tramadol should avoid:

  1. Drinking alcohol. Its effect in combination with the effect of Tramadol may trigger a dangerous decrease in the speed and depth of your breath.
  2. Using drugs that make you sleepy (cold medicine, other pain medications, muscle relaxants, and medicine for seizures, depression or anxiety, etc). Used together with Tramadol, these drugs may slow your breathing or cause extreme drowsiness.
  3. Driving, operating heavy machinery and performing other potentially hazardous activities that require you to be awake and alert at all times unless you understand what effect exactly Tramadol has on you.

Possible side effects of Tramadol.

You should seek for emergency medical help immediately in case you are experiencing any of the following symptoms of a severe allergic reaction: hives; difficulty breathing; swollen face, lips, tongue, or throat.

Stop using Tramadol and contact your doctor at once if you think you have any of the following serious side effects:

  • seizure (convulsions);
  • a red, blistering, peeling skin rash; or
  • shallow breathing, weak pulse.

You can keep on taking Tramadol (provided you contact your therapist as soon as you can) if you are experiencing any of the following minor side effects:

  • dizziness, sleepiness, weakness;
  • nausea, vomiting, constipation, decreased appetite;
  • blurred eyesight;
  • flushing (redness, the feeling of warmth or tingling); or
  • insomnia.

This is not the full list of possible side effects of Tramadol. Remember that you should contact your therapist at once if you notice some uncommon new or worsening old side effects become exceptionally bothersome.

Possible drug interaction with Tramadol.

There's a significant number of medicines that can increase the risk of a seizure in patients using Tramadol. Here are some of them:

  • an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam); or
  • an antidepressant such as amitriptyline (Elavil), citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Pamelor); paroxetine (Paxil), or sertraline (Zoloft).

Prior to taking Tramadol, you should also inform your therapist about the following drugs, should you be using any:

  • carbamazepine (Tegretol);
  • warfarin (Coumadin);
  • digoxin (Lanoxin, Lanoxicaps);
  • ketoconazole (Nizoral);
  • erythromycin (E-Mycin, E.E.S., Ery-Tab);
  • rifampin (Rifadin, Rimactane, Rifater);
  • St. John's wort;
  • quinidine (Quinaglute, Quinadex, Cardioquin, Quinora); or
  • drugs that are known to cause sleepiness (cold medicine, other pain medications, muscle relaxants, and medicine for seizures, depression or anxiety, etc).

If you are currently going through the course of therapy with any of the drugs stated above, you might not be able to use Tramadol at all, or your doctor will suggest a dosage adjustment or a series of tests carried out throughout the course of your treatment with Tramadol.

This listing doesn't include all possible drug interactions of Tramadol. Inform your doctor about all prescription and non-prescription medications that you are currently taking prior to the beginning of the therapy with Tramadol.

Sources of additional information about Tramadol.

If you happen to be in need of more detailed medical information about Tramadol, address your pharmacist.

What does Tramadol look like?

Tramadol is currently available in the medical market under a number of brand names, the most well-known of which are: Ultram and Ultram ER. Ask your pharmacist about everything that you might want to know about the medications containing Tramadol, especially if you are only planning to start the treatment with this drug.

  • Tramadol 50 mg - white, film-coated capsules.
  • Ultram ER 100 mg, 200 mg, 300 mg - white, round tablets designed for extended release of the drug.

Please, remember that Tramadol should always be stored out of the reach of children and away from pets. Since it is a drug of abuse, you should always keep it in a 100% secure place where other people won't be able to find and use it. Use Tramadol only for the indications prescribed.

PLEASE NOTE: This article is intended for informational purposes only. Neither does it contain any specific recommendations on how to use Tramadol, nor does it dispense any specific medical advice concerning any specific medical conditions. The information herein is not intended to be full and cover all possible uses, warnings, precautions, side effects, drug interactions and adverse effects of Tramadol. If you happen to have questions about Tramadol that this article has left unanswered, address your doctor, nurse, pharmacist or other healthcare provider with these questions.

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